Marrubium vulgare (white horehound or common horehound) Several modern scientific studies have been conducted on the usefulness of horehound. For example, a 2011 study concluded that the essential oil of M. vulgare contains potent antimicrobial and anticancer properties, while a 2012 study found marrubiin, one of the primary active compounds found in horehound, to possess antidiabetic, anti-atherogenic and anti-inflammatory properties.